Nucleofill

Nucleofill is a polynucleotide-based bio-restructuring line from Promoitalia, an Italian laboratory with a long track record in regenerative aesthetics. It has become one of the most recognized names in the fast-growing polynucleotide segment, where the aim is to repair and restructure the skin rather than fill it.

The gels are built on highly purified polynucleotides obtained through the brand’s PN-HPT process (Polynucleotides High Purification Technology). Once injected, they work on three levels: a lifting effect through fibroblast stimulation, an antioxidant effect through free radical scavenging, and deep hydration through the polynucleotides’ natural water-binding capacity.

The range is graded by density. Nucleofill Strong 1.5 ml is the classic facial formula for deep bio-restructuring of lax, photoaged skin. Nucleofill Medium 1.5 ml offers a softer profile for medium-density work, and Nucleofill Medium Plus 2 ml delivers the same approach in a larger volume format for broader treatment areas or combination protocols.

At Filladerm, licensed professionals can order Nucleofill Strong 1.5 ml, Nucleofill Medium 1.5 ml and Nucleofill Medium Plus 2 ml at wholesale prices, with verified European sourcing and fast worldwide shipping. Nucleofill sits at the heart of our Polynucleotides category, and combines naturally with the skin quality products in our Skinboosters range.